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Duocarmycin analog-3

ADC Synthesis Intermediate

Duocarmycin analog-3 is a key intermediate in antibody-drug conjugate (ADC) synthesis, functioning as a carbamate prodrug. This compound plays a critical role in the development of targeted cancer therapeutics, facilitating the combination of antibodies with cytotoxic agents to enhance selectivity and efficacy. Researchers can utilize Duocarmycin analog-3 to advance their studies in drug formulation and the optimization of ADCs for improved therapeutic outcomes.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1049811-71-3
Applications	ADC Synthesis Intermediate
Formula	C₃₅H₃₃ClN₆O₄
Molecular Weight	637.13
SMILES	ClC[C@H]1C2=C(C=C(C3=CC=CC=C32)OC(N4CCN(CC4)C)=O)N(C1)C(C5=CC6=CC(NC(C7=CC=C(C=C7)N)=O)=CC=C6N5)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.