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Biological Activity
Duocarmycin GA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin GA can be used against multi-drug resistant cell lines.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.97 mL | 104.83 mL | 209.67 mL |
| 0.5 mM | 4.19 mL | 20.97 mL | 41.93 mL |
| 1 mM | 2.1 mL | 10.48 mL | 20.97 mL |
| 5 mM | 0.42 mL | 2.1 mL | 4.19 mL |
*The above data is based on the productmolecular weight 476.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18546 |
|---|---|
| CAS No. | 1613286-59-1 |
| Formula | C26H25ClN4O3 |
| M. Wt | 476.95 |
| Purity | >98% |
| SMILES | O=C(NC1=CC2=C(C=C1)C=C(C(N3C[[email protected]@H](CCl)C4=C3C=C(O)C5=CC=CC=C45)=O)N2)CN(C)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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