DW14800

Catalog No.: A18491
PRMT5 inhibitor
DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 17 nM. DW14800 reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. Anti-cancer activity.
Grouped product items
Product Name Price Stock Qty
DW14800 5mg
$350.00
In stock
DW14800 10mg
$650.00
In stock
DW14800 50mg
$2,000.00
In stock
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Biological Activity
Discription DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 17 nM. DW14800 reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. Anti-cancer activity.
Targets
Target Value
Product Information
Catalog Num A18491
Formula C31H36N4O3
Molecular Weight 512.64
CAS Number 2243709-60-4
SMILES CN(C)C1=CC=C(C(N2CCC(C=C(C(NCC(O)CN3CC(C=CC=C4)=C4CC3)=O)C=C5)=C5C2)=O)C=C1
Synonyms DW 14800, DW-14800
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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