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DX-8951 Hydroxy-acid

Nucleic Acid Prodrug

DX-8951 Hydroxy-acid is a nucleic acid prodrug known for its role in enhancing intracellular ATP levels. It activates the AMPK signaling pathway by increasing the AMP/ATP ratio, leading to improved mitochondrial function and elevated antioxidant capacity while reducing reactive oxygen species (ROS) levels. Research indicates that DX-8951 Hydroxy-acid exhibits significant anti-aging and longevity effects, as demonstrated in human fibroblast and nematode models.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	276680-63-8
Applications	Nucleic Acid Prodrug
Formula	C₂₄H₂₄FN₃O₅
Molecular Weight	453.46
SMILES	FC1=CC2=NC3=C(CN4C3=CC([C@@](C(O)=O)(O)CC)=C(CO)C4=O)C([C@@H](N)CC5)=C2C5=C1C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.