Fig. 1 · Structure
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Dynamin IN-2
Dynamin Inhibitor
Dynamin IN-2 is a potent inhibitor of dynamin I, targeting its GTPase activity with an IC50 of 1.0 μM. This compound effectively interferes with clathrin-mediated endocytosis (CME), exhibiting an IC50 of 9.5 μM. Dynamin IN-2 is a valuable tool for investigating the role of dynamin in cellular processes and the mechanisms of endocytosis in biochemical research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1345853-49-7 |
| Applications | Dynamin Inhibitor |
| Formula | C22H21ClN2O |
| Molecular Weight | 364.87 |
| SMILES | ClC(C=C1)=CC=C1CNCC(CN2C3=CC=CC=C3C4=CC=CC=C42)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.