Dyrk1A/α-synuclein-IN-1 is an inhibitor targeting both Dyrk1A and α-synuclein aggregation, demonstrating IC50 values of 177 nM and 10.5 µM, respectively. This dual-action compound is noted for its potential neuroprotective effects and favorable central nervous system penetration. It is applicable in research surrounding neurodegenerative diseases and the modulation of protein aggregation pathways.
Dyrk1A/α-synuclein-IN-1 is an inhibitor targeting both Dyrk1A and α-synuclein aggregation, demonstrating IC50 values of 177 nM and 10.5 µM, respectively. This dual-action compound is noted for its potential neuroprotective effects and favorable central nervous system penetration. It is applicable in research surrounding neurodegenerative diseases and the modulation of protein aggregation pathways.
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