Dyrk1A/α-synuclein-IN-2

Catalog No.: A35088
Dyrk1A/α-syn Inhibitor
Dyrk1A/α-synuclein-IN-2 is an effective inhibitor targeting both Dyrk1A and α-synuclein aggregation, with an IC50 value of 7.8 µM for α-synuclein. This compound demonstrates significant potential for central nervous system (CNS) penetration and exhibits neuroprotective properties. It is particularly useful in research focused on neurodegenerative diseases and understanding the molecular mechanisms underlying α-synuclein pathology.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDyrk1A/α-synuclein-IN-2 is an effective inhibitor targeting both Dyrk1A and α-synuclein aggregation, with an IC50 value of 7.8 µM for α-synuclein. This compound demonstrates significant potential for central nervous system (CNS) penetration and exhibits neuroprotective properties. It is particularly useful in research focused on neurodegenerative diseases and understanding the molecular mechanisms underlying α-synuclein pathology.
Product Information
Catalog NumA35088
FormulaC21H16N4O4S
Molecular Weight420.44
CAS Number2789711-66-4
SMILESO=C(NC1=NC2=C(S1)C=C(C=C2)O)NC3=CC=C(C=C3)NC(C4=CC(O)=CC=C4)=O
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