Dyrk1A/B-IN-1 is a selective inhibitor targeting DYRK1A and DYRK1B, exhibiting Kis of 67.8 nM and 237.9 nM, and IC50s of 1.1 μM and 0.8 μM, respectively. This compound is cell-permeable and non-toxic to human cells, making it suitable for investigating the cellular functions of DYRK1A and DYRK1B. Dyrk1A/B-IN-1 is valuable for research applications focused on understanding the role of these kinases in various pathological conditions.
Dyrk1A/B-IN-1 is a selective inhibitor targeting DYRK1A and DYRK1B, exhibiting Kis of 67.8 nM and 237.9 nM, and IC50s of 1.1 μM and 0.8 μM, respectively. This compound is cell-permeable and non-toxic to human cells, making it suitable for investigating the cellular functions of DYRK1A and DYRK1B. Dyrk1A/B-IN-1 is valuable for research applications focused on understanding the role of these kinases in various pathological conditions.
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