Dyrk1A-IN-1 is a selective inhibitor of Dyrk1A kinase activity, demonstrating an IC50 of 119 nM. This compound effectively inhibits the aggregation of tau and α-synuclein oligomers, making it a valuable tool for investigating neurodegenerative diseases. Its capacity to modulate kinase activity and prevent protein aggregation highlights its potential in studying pathways associated with tauopathies and synucleinopathies.
Dyrk1A-IN-1 is a selective inhibitor of Dyrk1A kinase activity, demonstrating an IC50 of 119 nM. This compound effectively inhibits the aggregation of tau and α-synuclein oligomers, making it a valuable tool for investigating neurodegenerative diseases. Its capacity to modulate kinase activity and prevent protein aggregation highlights its potential in studying pathways associated with tauopathies and synucleinopathies.
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