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Dyrk1A-IN-17

Multi-kinase Inhibitor

Dyrk1A-IN-17 is an orally active multi-kinase inhibitor that effectively crosses the blood-brain barrier. This compound targets and inhibits multiple kinases, including ABL1, DYRK1A, GSK3β, and LRRK2, leading to a reduction in the phosphorylation of α-synuclein and stabilization of microtubules. Dyrk1A-IN-17 is relevant for research focused on neurodegenerative disorders, including Parkinson's disease and Alzheimer's disease.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2201083-51-2
Applications	Multi-kinase Inhibitor
Formula	C₁₇H₁₄ClN₅
Molecular Weight	323.78
SMILES	NC1=NC2=C(C(N(C3=CC=CC=C3)C)=N1)C4=C(C=CC=C4Cl)N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.