Dyrk1A-IN-8

Catalog No.: A35095
Dyrk1A Inhibitor
Dyrk1A-IN-8 is a specific inhibitor of Dyrk1A, exhibiting an IC50 of 209 nM. This compound is significant for its potential applications in the study of neurodegenerative diseases by modulating kinase activity. Research involving Dyrk1A-IN-8 can provide insights into therapeutic strategies for conditions associated with dysregulated kinase signaling.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDyrk1A-IN-8 is a specific inhibitor of Dyrk1A, exhibiting an IC50 of 209 nM. This compound is significant for its potential applications in the study of neurodegenerative diseases by modulating kinase activity. Research involving Dyrk1A-IN-8 can provide insights into therapeutic strategies for conditions associated with dysregulated kinase signaling.
Product Information
Catalog NumA35095
FormulaC17H21N3O
Molecular Weight283.37
CAS Number101578-13-6
SMILESCC1=NC=CC2=C1N(C3=CC(OC)=CC=C32)CCN(C)C
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