DYRKs-IN-1 is a potent inhibitor of dual-specificity tyrosine-phosphorylation-regulated kinases (DYRKs), effectively targeting DYRK1A and DYRK1B with IC50 values of 5 nM and 8 nM, respectively. This compound demonstrates significant antitumor activity, making it a valuable tool for research in cancer biology and potential therapeutic applications. Its specificity and efficacy support further investigations into the role of DYRKs in cell signaling and tumor progression.
DYRKs-IN-1 is a potent inhibitor of dual-specificity tyrosine-phosphorylation-regulated kinases (DYRKs), effectively targeting DYRK1A and DYRK1B with IC50 values of 5 nM and 8 nM, respectively. This compound demonstrates significant antitumor activity, making it a valuable tool for research in cancer biology and potential therapeutic applications. Its specificity and efficacy support further investigations into the role of DYRKs in cell signaling and tumor progression.
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