DYRKs-IN-2 is a potent inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family members, exhibiting IC50 values of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. This compound demonstrates significant antitumor activity, making it a valuable tool for cancer research. Its selective inhibition of DYRKs enables exploration of their roles in cellular signaling pathways and therapeutic potential in oncology.
DYRKs-IN-2 is a potent inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family members, exhibiting IC50 values of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. This compound demonstrates significant antitumor activity, making it a valuable tool for cancer research. Its selective inhibition of DYRKs enables exploration of their roles in cellular signaling pathways and therapeutic potential in oncology.
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