Fig. 1 · Structure
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ε-Biotinamidocaproyl-β-alanyl-β-alanyl-lisinopril
ACE Inhibitor
ε-Biotinamidocaproyl-β-alanyl-β-alanyl-lisinopril is an angiotensin-converting enzyme (ACE) inhibitor that exhibits potent biological activity in modulating blood pressure and cardiovascular function. This biotinylated derivative of lisinopril features a unique chemical structure that allows for concurrent binding to both ACE and streptavidin. This dual binding capability facilitates the isolation and purification of ACE using streptavidin-agarose beads, making it a valuable tool for research in cardiovascular studies and enzyme inhibition assays.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 130007-47-5 |
| Applications | ACE Inhibitor |
| Formula | C37H56N6O8S |
| Molecular Weight | 744.94 |
| SMILES | O=C(O)[C@H]1N(C([C@H](CCCCNC(CCCCCNC(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O)=O)NC(C(O)=O)CCC4=CC=CC=C4)=O)CCC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.