Fig. 1 · Structure

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(E)-CLX-0921

E Isomer

(E)-CLX-0921 is the E isomer of CLX-0921, serving as a selective PPARγ agonist with an IC50 of 1.54 μM. This compound exhibits significant antihyperglycemic activity, making it a valuable tool for research into type 2 diabetes and metabolic disorders. Its oral bioavailability facilitates in vivo studies, contributing to a deeper understanding of PPARγ modulation in glucose homeostasis.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 606932-81-4
Applications E Isomer
Formula C28H25NO7S
Molecular Weight 519.57
SMILES
COC1=CC(OC)=CC(/C=C(C2=CC=C(C=C2)OC3=CC=C(C=C3)CC4SC(NC4=O)=O)/C(OC)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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