Fig. 1 · Structure
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(E)-SI-2
anticancer agent
(E)-SI-2 is an isomer of SI-2 that functions as an inhibitor of the steroid receptor coactivator SRC-3. This compound exhibits significant anticancer activity and has been shown to enhance the population of cytotoxic immune cells in murine models of breast cancer. Its potential applications include investigations into cancer immunotherapy and the modulation of steroid signaling pathways in cancer contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 380537-35-9 |
| Applications | anticancer agent |
| Formula | C15H15N5 |
| Molecular Weight | 265.31 |
| Synonyms | (E)-EPH 116 |
| SMILES | CN1C2=CC=CC=C2N=C1N/N=C(C3=CC=CC=N3)\C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.