Fig. 1 · Structure
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(E/Z)-Mirin
Mre11-Rad50-Nbs1 Complex Inhibitor
(E/Z)-Mirin is a dual-configuration inhibitor targeting the Mre11-Rad50-Nbs1 (MRN) complex. It effectively inhibits MRN-dependent activation of ATM (Ataxia telangiectasia mutated) without interfering with ATM kinase activity. This compound is valuable for research applications exploring DNA damage response mechanisms and studying the role of the MRN complex in genomic stability and repair processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 299953-00-7 |
| Applications | Mre11-Rad50-Nbs1 Complex Inhibitor |
| Formula | C10H8N2O2S |
| Molecular Weight | 220.25 |
| SMILES | O=C1N=C(N)S/C1=C/C2=CC=C(O)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.