Fig. 1 · Structure
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(E/Z)-NiCur
Active Isomer
(E/Z)-NiCur is the active isomer of NiCur, functioning as a potent inhibitor of CBP histone acetyltransferase (HAT). By targeting this enzyme, (E/Z)-NiCur plays a significant role in modulating histone acetylation, thereby influencing gene expression and cellular processes. This compound is useful in research applications focused on epigenetics and cancer biology, providing insights into the role of histone modifications in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 63476-70-0 |
| Applications | Active Isomer |
| Formula | C22H16N2O |
| Molecular Weight | 324.38 |
| SMILES | N#CC1=CC=CC(/C=C2C(/C(CCC/2)=C/C3=CC(C#N)=CC=C3)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.