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E10i-494

Lipid

E10i-494 is an ionizable cationic branched endosomal disruptor (BEND) lipid designed for effective lipid nanoparticle (LNP) formation. This compound significantly enhances transfection efficiency, making it a valuable tool for mRNA delivery applications in vitro. Its unique properties facilitate improved cellular uptake and endosomal escape, supporting advanced research in gene therapy and vaccine development.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3031773-77-7
Applications	Lipid
Formula	C₈₉H₁₈₃N₅O₇
Molecular Weight	1435.43
SMILES	OC(CCCCCCCCCCC(C)C)CN(CCN1CCN(CC1)CCOCCN(CC(CCCCCCCCCCC(C)C)O)CC(CCCCCCCCCCC(C)C)O)CCOCCN(CC(CCCCCCCCCCC(C)C)O)CC(CCCCCCCCCCC(C)C)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.