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E3 ligase Ligand 24

Potent Ligand DCAF15

E3 Ligase Ligand 24 is a potent ligand for the E3 ligase DCAF15, exhibiting an IC50 of 0.053 μM. Its high selectivity and strong binding properties make it an essential tool for investigating targeted protein degradation pathways. This compound is valuable for researchers exploring the modulation of protein homeostasis and the development of novel therapeutics.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3038773-47-3
Applications	Potent Ligand DCAF15
Formula	C₂₁H₂₂Cl₂N₄O₅S
Molecular Weight	513.39
SMILES	CC1=C(C(N2CCC(C(NC)=O)CC2)=O)OC(S(=O)(NC3=C(NC=C4Cl)C4=C(Cl)C=C3)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.