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E3 ligase Ligand 31

Ligand for E3 Ligase

E3 Ligase Ligand 31 is a specific ligand for E3 ubiquitin ligases, facilitating targeted protein degradation via the ubiquitin-proteasome system. This compound is instrumental in the synthesis of PTOTAC HSD17B13 degrader 1, making it a valuable tool for research in protein homeostasis and related therapeutic applications. Its utility in studying E3 ligase interactions offers insights into the modulation of protein levels in cellular and biochemical contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2357114-13-5
Applications	Ligand for E3 Ligase
Formula	C₁₆H₁₇N₃O₄
Molecular Weight	315.32
SMILES	O=C1N(C2C(NC(CC2)=O)=O)C3=CC=C(CCC([H])=O)C=C3N1C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.