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E3 ligase Ligand 34

E3 Ligase Ligand

E3 Ligase Ligand 34 is an E3 ligase ligand that facilitates targeted protein degradation through the development of PROTACs. This compound is integral to the synthesis of PROTAC SMARCA2/4-degrader-35, enabling the selective degradation of SMARCA2 and SMARCA4 proteins. Its application in research supports the exploration of protein homeostasis and regulation pathways within cellular processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2931870-73-2
Applications	E3 Ligase Ligand
Formula	C₃₁H₄₀N₆O₅
Molecular Weight	576.69
SMILES	CC(C)[C@@H](C(N1C[C@H](O)C[C@H]1C(N[C@@H](C)C2=CC=C(C3=CC=NN3C)C=C2)=O)=O)C4=CC(N(CC5)CCC5C=O)=NO4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.