Fig. 1 · Structure

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E3 ligase Ligand 41

Ligand for DCAF16

E3 Ligase Ligand 41 is a selective ligand for the E3 ubiquitin ligase DCAF16. It plays a crucial role in the regulation of ubiquitination processes, which are important for protein degradation and cellular signaling. This compound can be utilized in research to investigate the mechanisms of protein turnover and to develop targeted therapies. Additionally, E3 Ligase Ligand 41 can be linked to SLF through a suitable linker to create KB03-SLF, expanding its utility in biochemical studies.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2375196-68-0
Applications Ligand for DCAF16
Formula C13H12ClF3N2O4
Molecular Weight 352.69
SMILES
OC(CCNC(C1=CC(NC(CCl)=O)=CC(C(F)(F)F)=C1)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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