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E3 ligase Ligand 42

Ligands for E3 Ligase

E3 ligase Ligand 42 is an E3 ubiquitin ligase ligand designed for targeted protein degradation applications. It can be conjugated to a target protein ligand via a linker, facilitating the synthesis of PROTAC AR Degrader-6. This compound effectively induces ubiquitination and subsequent degradation of proteins associated with cancer progression, making it a valuable tool for research in cancer biology and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2753651-18-0
Applications	Ligands for E3 Ligase
Formula	C₁₃H₁₀FN₃O₃
Molecular Weight	275.24
SMILES	O=C(C(N(N=CC1=C2C=CC(F)=C1)C2=O)CC3)NC3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.