Fig. 1 · Structure

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E3 ligase Ligand 43

E3 Ubiquitin Ligase Ligand

E3 Ligase Ligand 43 functions as a ligand for E3 ubiquitin ligase ACBI3. This compound is essential for the synthesis of Proteolysis Targeting Chimeras (PROTACs), allowing for targeted protein degradation. Its application is significant in cellular studies investigating protein turnover, signaling pathways, and disease mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2821795-71-3
Applications E3 Ubiquitin Ligase Ligand
Formula C22H28N6O4S
Molecular Weight 472.56
SMILES
[N-]=[N+]=N[C@@H](C(C)C)C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)CO)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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