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E3 ligase Ligand 49

E3 Ubiquitin Ligase Ligand

E3 ligase Ligand 49 is an E3 ubiquitin ligase ligand that plays a critical role in the development of PROTAC (Proteolysis Targeting Chimeras) technology. This compound is specifically designed for the synthesis of PROTACs targeting XPO1, facilitating targeted protein degradation in various biological contexts. Its application is particularly relevant in studies focusing on protein regulation and degradation pathways, providing valuable insights into cellular processes and disease mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	1911013-66-5
Applications	E3 Ubiquitin Ligase Ligand
Formula	C₁₃H₁₅N₃O₄
Molecular Weight	277.28
SMILES	COC1=C(C(NC2C(NC(CC2)=O)=O)=O)C=CC=C1N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.