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E3 ligase Ligand 54

Cereblon Ligand

E3 Ligase Ligand 54 is a selective ligand for the E3 ubiquitin ligase Cereblon, playing a crucial role in targeted protein degradation. This compound facilitates the synthesis of PROTAC Degrader SJ44236, enabling the investigation of protein homeostasis and therapeutic strategies in cancer research. Its utility in studying ubiquitin-proteasome pathways makes it a valuable tool for drug discovery and development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2413038-90-9
Applications	Cereblon Ligand
Formula	C₁₅H₁₉N₃O₂
Molecular Weight	273.33
SMILES	O=C1NC(=O)C(C2=CC=C(C=C2)N3CCNCC3)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.