Fig. 1 · Structure
Documents & Downloads
E3 ligase Ligand 56
Cereblon Ligand
E3 Ligase Ligand 56 is a specific ligand for the E3 ubiquitin ligase Cereblon, facilitating targeted protein degradation through proteolysis-targeting chimeras (PROTACs). This compound is instrumental in the synthesis of PROTAC CDK9 degrader-11, supporting research in targeted degradation mechanisms and their applications in cellular processes. Its utility in developing novel therapeutics makes it a valuable reagent for studies in oncology and pharmacology.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 1472731-41-1 |
| Applications | Cereblon Ligand |
| Formula | C11H13N3O2 |
| Molecular Weight | 219.24 |
| SMILES | O=C(C(NC1=CC=CC(N)=C1)CC2)NC2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.