Documents & Downloads

E3 ligase Ligand 66

E3 Ligase Ligand

E3 ligase Ligand 66 is an E3 ligase ligand designed to specifically recruit inhibitor of apoptosis (IAP) proteins. This compound facilitates targeted protein degradation through the formation of PROTACs when conjugated with ligands such as SARS-CoV-2 Mpro ligand 1, enabling researchers to manipulate protein levels in cellular systems. Its applications extend to investigations in degradation pathways and therapeutic strategies against diseases, including viral infections.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2416133-92-9
Applications	E3 Ligase Ligand
Formula	C₂₆H₃₄N₄O₄S
Molecular Weight	498.64
SMILES	C[C@@H](C(N[C@@H](C1CCCCC1)C(N2CCC[C@H]2C3=NC(C(C4=CC(O)=CC=C4)=O)=CS3)=O)=O)NC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.