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E3 ligase Ligand 68

E3 Ligase Ligand

E3 Ligase Ligand 68 is an E3 ligase ligand utilized in the development of PROTAC (proteolysis-targeting chimeras) molecules. It facilitates targeted protein degradation by enabling the conjugation of an E3 ligase to a ligand that binds the protein of interest. This reagent is essential for research applications aimed at studying protein homeostasis, disease mechanisms, and therapeutic interventions involving targeted protein degradation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	1466558-44-0
Applications	E3 Ligase Ligand
Formula	C₃₄H₃₉N₅O₆
Molecular Weight	613.70
SMILES	CC(N([C@H]([C@@H](C1=O)NC([C@H](C)N(C)C(OC(C)(C)C)=O)=O)C)C2=CC(C#N)=CC=C2N1CC3=C(OC)C=CC4=C3C=CC=C4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.