E3 ligase Ligand 68

Catalog No.: A80594
E3 Ligase Ligand
E3 Ligase Ligand 68 is an E3 ligase ligand utilized in the development of PROTAC (proteolysis-targeting chimeras) molecules. It facilitates targeted protein degradation by enabling the conjugation of an E3 ligase to a ligand that binds the protein of interest. This reagent is essential for research applications aimed at studying protein homeostasis, disease mechanisms, and therapeutic interventions involving targeted protein degradation.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
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Biological Activity
DescriptionE3 Ligase Ligand 68 is an E3 ligase ligand utilized in the development of PROTAC (proteolysis-targeting chimeras) molecules. It facilitates targeted protein degradation by enabling the conjugation of an E3 ligase to a ligand that binds the protein of interest. This reagent is essential for research applications aimed at studying protein homeostasis, disease mechanisms, and therapeutic interventions involving targeted protein degradation.
Product Information
Catalog NumA80594
FormulaC34H39N5O6
Molecular Weight613.70
CAS Number1466558-44-0
SMILESCC(N([C@H]([C@@H](C1=O)NC([C@H](C)N(C)C(OC(C)(C)C)=O)=O)C)C2=CC(C#N)=CC=C2N1CC3=C(OC)C=CC4=C3C=CC=C4)=O
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