Fig. 1 · Structure

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E3 ligase Ligand 7

Ligand for E3 Ligase

E3 ligase Ligand 7 is a selective ligand for E3 ligase, facilitating targeted protein degradation through the formation of PROTACs (proteolysis-targeting chimeras). This compound serves as a key building block for the synthesis of PROTAC BET Degrader-12, enabling researchers to study the modulation of BET protein functions. E3 ligase Ligand 7 is valuable for applications in drug discovery and development, particularly in exploring therapeutic strategies for diseases associated with aberrant protein levels.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 37630-54-9
Applications Ligand for E3 Ligase
Formula C14H9NO2
Molecular Weight 223.23
SMILES
O=C(O)/C(C#N)=C/C1=CC=C2C=CC=CC2=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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