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E3 ligase Ligand 77

Ligands for E3 Ligase

E3 Ligase Ligand 77 is a ligand targeting the CRBN type E3 ubiquitin ligase. This compound facilitates the synthesis of PROTACs, including PROTAC RET Degrader 1. Its primary application is in the development of targeted protein degradation strategies, enabling researchers to investigate and manipulate protein levels in various biological contexts. E3 Ligase Ligand 77 serves as a valuable tool in cellular and molecular biology studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2259850-62-7
Applications	Ligands for E3 Ligase
Formula	C₁₁H₁₁FN₂O₂
Molecular Weight	222.22
SMILES	FC1=CC=CC(NC2CCC(NC2=O)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.