Fig. 1 · Structure

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E3 Ligase Ligand-linker Conjugate 195

CRBN Ligand-Linker Conjugates

E3 Ligase Ligand-linker Conjugate 195 is a conjugate that targets cereblon (CRBN) through its ligand component. This compound facilitates the development of Proteolysis Targeting Chimeras (PROTACs) by providing a functional linker necessary for targeted protein degradation. It is suitable for research applications investigating novel therapeutic strategies in protein modulation and degradation pathways.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3065496-07-0
Applications CRBN Ligand-Linker Conjugates
Formula C23H25N3O5
Molecular Weight 423.46
SMILES
CN1C(C(N(C1=O)C2C(NC(CC2)=O)=O)=CC=C3)=C3C#CCO[C@@H](CC4)CC[C@H]4C=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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