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E3 Ligase Ligand-linker Conjugate 227

E3 Ligase Ligand-linker Conjugate

E3 Ligase Ligand-Linker Conjugate 227 is designed to target E3 ligases, combining CRBN ligand-1 with a specific linker. This conjugate facilitates the creation of PROTAC molecules by linking to the BRD9 ligand-12, enabling targeted protein degradation. It is valuable for research in the field of targeted therapy, providing insights into protein regulation and degradation pathways.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3039540-25-2
Applications	E3 Ligase Ligand-linker Conjugate
Formula	C₂₆H₃₉N₅O₄
Molecular Weight	485.62
SMILES	O=C(C(CC1)NC(C=C2)=CC=C2N3CCN(CC4CCN(C(OC(C)(C)C)=O)CC4)CC3)NC1=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.