E3 ligase Ligand PG

Catalog No.: A80484
E3 Ligase Ligand
E3 ligase Ligand PG is a selective ligand targeting the CRBN E3 ubiquitin ligase, exhibiting strong binding affinity with an IC50 of 2.191 μM. This compound is suitable for applications involving the recruitment of the CRBN protein, facilitating the development of proteolysis-targeting chimeras (PROTACs). E3 ligase Ligand PG can be utilized in conjunction with BMS-202 to form PROTAC PD-L1 degrader-1, enabling targeted degradation of specific proteins for therapeutic research purposes.
Grouped product items
Size Price Stock Qty
50mg
$25.00
In stock
100mg
$40.00
In stock
250mg
$75.00
In stock
500mg
$105.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
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Biological Activity
DescriptionE3 ligase Ligand PG is a selective ligand targeting the CRBN E3 ubiquitin ligase, exhibiting strong binding affinity with an IC50 of 2.191 μM. This compound is suitable for applications involving the recruitment of the CRBN protein, facilitating the development of proteolysis-targeting chimeras (PROTACs). E3 ligase Ligand PG can be utilized in conjunction with BMS-202 to form PROTAC PD-L1 degrader-1, enabling targeted degradation of specific proteins for therapeutic research purposes.
Product Information
Catalog NumA80484
FormulaC11H11NO2
Molecular Weight189.21
CAS Number14149-34-9
SMILESO=C1CCC(C(N1)=O)C2=CC=CC=C2
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