Fig. 1 · Structure
Documents & Downloads
Ebelactone A
Esterase Inhibitor
Ebelactone A is a mycolic acid β-lactone that acts as a potent esterase inhibitor. It demonstrates significant inhibitory activity against multiple enzymes, including lipase and fMet aminopeptidase, with IC50 values of 56 μM and 3 μM respectively. Furthermore, Ebelactone A shows efficacy against PNBase and cutinase, with IC50s of 8 μM and 7.5 μM. This compound also provides protective effects against the plant pathogen Erysiphe graminis, making it valuable for studies in enzymology and plant protection research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 76808-16-7 |
| Applications | Esterase Inhibitor |
| Formula | C20H34O4 |
| Molecular Weight | 338.48 |
| SMILES | CC[C@@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C[C@@H]([C@@]1([H])[C@@H](C(O1)=O)C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.