Fig. 1 · Structure
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EC5026
sEH Inhibitor
EC5026 is a novel, orally active soluble Epoxide Hydrolase (sEH) inhibitor. It demonstrates significant efficacy in models of inflammatory and neuropathic pain, making it a valuable tool for research in pain management and related disorders. This first-in-class compound serves as an important resource for studying the modulation of pain pathways and exploring therapeutic strategies targeting sEH.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1809885-32-2 |
| Applications | sEH Inhibitor |
| Formula | C18H23F4N3O3 |
| Molecular Weight | 405.39 |
| Synonyms | BPN-19186 |
| SMILES | O=C(NC1CCN(C([C@@H](C)CC)=O)CC1)NC2=CC=C(OC(F)(F)F)C(F)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.