Fig. 1 · Structure
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EcDsbB-IN-10
EcDsbB Inhibitor
EcDsbB-IN-10 is a potent inhibitor of the EcDsbB enzyme, exhibiting a Ki value of 0.8 nM and an IC50 of 18.85 nM. This compound is essential for studies investigating disulfide bond formation in E. coli and can be utilized in research focused on bacterial protein folding and redox homeostasis. Its high specificity and efficacy make it a valuable tool for exploring bacterial virulence and potential therapeutic targets.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 112749-52-7 |
| Applications | EcDsbB Inhibitor |
| Formula | C11H7Cl3N2O |
| Molecular Weight | 289.55 |
| SMILES | O=C1C(Cl)=C(C=NN1CC2=CC=CC=C2Cl)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.