Fig. 1 · Structure

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EDDP perchlorate

Methadone Metabolite

EDDP perchlorate is the N-desmethyl metabolite of Methadone, primarily generated by intestinal and hepatic processes, as well as by cytochrome P450 (CYP) 3A4 enzymatic activity. This compound serves as a valuable biomarker in pharmacokinetic studies and is utilized in research concerning opioid metabolism and related therapeutic effects. Its role in understanding the pharmacodynamics of Methadone permits deeper insights into opioid receptor interactions and metabolic pathways.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 31161-17-8
Applications Methadone Metabolite
Formula C20H24ClNO4
Molecular Weight 377.86
SMILES
O=Cl(=O)([O-])=O.C[N+](C(C1)C)=C(CC)C1(C2=CC=CC=C2)C3=CC=CC=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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