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$0.00 Biological Activity
Edotecarin is a potent inhibitor of topoisomerase I that can induces single-strand DNA cleavage, with IC50 of 50 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.43 mL | 82.16 mL | 164.33 mL |
| 0.5 mM | 3.29 mL | 16.43 mL | 32.87 mL |
| 1 mM | 1.64 mL | 8.22 mL | 16.43 mL |
| 5 mM | 0.33 mL | 1.64 mL | 3.29 mL |
*The above data is based on the productmolecular weight 608.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21233 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 608.55 |
| Formula | C29H28N4O11 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 174402-32-5 |
| Synonyms | J 107088; PF 804950 |
| SMILES | O=C1N(NC(CO)CO)C(C2=C1C3=C(C4=C2C5=C(N4[[email protected]]6[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]@H](CO)O6)O)O)O)C=C(O)C=C5)NC7=C3C=CC(O)=C7)=O |
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