Edotecarin

Catalog No.: A21233

Topoisomerase I inhibitor

Edotecarin

Edotecarin Chemical Structure

CAS NO. 174402-32-5

Edotecarin is a potent inhibitor of topoisomerase I that can induces single-strand DNA cleavage, with IC50 of 50 nM.

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1 mg
$3,888.00
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Biological Activity

Edotecarin is a potent inhibitor of topoisomerase I that can induces single-strand DNA cleavage, with IC50 of 50 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.43 mL 82.16 mL 164.33 mL
0.5 mM 3.29 mL 16.43 mL 32.87 mL
1 mM 1.64 mL 8.22 mL 16.43 mL
5 mM 0.33 mL 1.64 mL 3.29 mL

*The above data is based on the productmolecular weight 608.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21233
Actions Inhibitor
M. Wt 608.55
Formula C29H28N4O11
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 174402-32-5
Synonyms J 107088; PF 804950
SMILES O=C1N(NC(CO)CO)C(C2=C1C3=C(C4=C2C5=C(N4[[email protected]]6[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]@H](CO)O6)O)O)O)C=C(O)C=C5)NC7=C3C=CC(O)=C7)=O

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