Fig. 1 · Structure
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EDTA-AM
EDTA Membrane-Permeant Form
EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) serves as a membrane-permeant variant of the chelating agent EDTA. Upon passive uptake by live cells, cytoplasmic esterases hydrolyze the AM esters, resulting in the release of active EDTA that sequesters metal ions intracellularly. EDTA-AM is instrumental in research focusing on cell cycle dynamics, particularly in studying mitotic arrest and chromosome decondensation processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 162303-59-5 |
| Applications | EDTA Membrane-Permeant Form |
| Formula | C22H32N2O16 |
| Molecular Weight | 580.49 |
| Synonyms | EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester |
| SMILES | O=C(C)OCOC(CN(CCN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.