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EED-IN-3

EED inhibitor

EED-IN-3 is a small molecule inhibitor of the embryonic ectoderm development (EED) protein, targeting the Polycomb Repressive Complex 2 (PRC2) with an IC50 of 0.62 μM. This compound effectively downregulates histone H3 trimethylation at lysine 27 (H3K27me3) and demonstrates selective activity against PC3 prostate cancer cells, exhibiting an IC50 of 3.69 μM. EED-IN-3 is suitable for research applications focused on prostate cancer progression and therapeutic intervention.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3051817-48-9
Applications	EED inhibitor
Formula	C₂₅H₂₉N₃O₅
Molecular Weight	451.51
SMILES	COC1=CC=C(C=C1)C2=NN(C(C(C(NCCCOC(C)C)=O)=C2)=O)C3=CC=C(C=C3)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.