Fig. 1 · Structure
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EED226-COOH
Ligand For Target Protein
EED226-COOH is an EED226-derived ligand that targets the EED protein, facilitating the formation of PROTACs. This compound effectively binds to a VHL ligand through a linker, leading to the degradation of the PRC2 complex. EED226-COOH is valuable for research applications focused on targeted protein degradation and studying the roles of PRC2 in various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2467965-71-3 |
| Applications | Ligand For Target Protein |
| Formula | C17H13N5O3 |
| Molecular Weight | 335.32 |
| SMILES | OC(C1=CC=C(C=C1)C2=CN=C(N3C2=NN=C3)NCC4=CC=CO4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.