Fig. 1 · Structure
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EF-5
Hypoxia Labeling Agent
EF-5 (2-Nitroimidazole) targets hypoxic regions within tissues, serving as a powerful hypoxia labeling agent. It selectively binds to low-oxygen conditions in cellular environments, allowing for the visualization and quantification of hypoxic cells. This compound is widely utilized in cancer research and studies related to tumor microenvironments, facilitating a better understanding of oxygen deprivation effects on cellular behavior and treatment responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 152721-37-4 |
| Applications | Hypoxia Labeling Agent |
| Formula | C8H7F5N4O3 |
| Molecular Weight | 302.16 |
| SMILES | O=C(NCC(F)(F)C(F)(F)F)CN1C=CN=C1[N+]([O-])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.