Fig. 1 · Structure
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Efavirenz-13C6
Stable Isotope
Efavirenz-13C6 is a stable isotope-labeled variant of Efavirenz, a strong inhibitor of HIV-1 reverse transcriptase, exhibiting a Ki of 2.93 nM. This compound demonstrates an IC95 of 1.5 nM, effectively inhibiting the replication of HIV-1 in cultured cells. Efavirenz-13C6 is valuable for studies in pharmacokinetics, metabolism, and HIV research applications requiring precise tracking of drug distribution and activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1261394-62-0 |
| Applications | Stable Isotope |
| Formula | C813C6H9ClF3NO2 |
| Molecular Weight | 321.63 |
| Synonyms | DMP 266-13C6; EFV-13C6; L-743726-13C6 |
| SMILES | FC(F)(F)[C@@]1([13C]2=[13CH][13C](Cl)=[13CH][13CH]=[13C]2NC(O1)=O)C#CC3CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.