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EFdA-TP

Nucleoside RT Inhibitor

EFdA-TP is a potent nucleoside reverse transcriptase inhibitor that functions as both an immediate and delayed chain terminator during RT-catalyzed DNA synthesis. This compound is effective in inhibiting HIV-1 reverse transcriptase through multiple mechanisms, making it a valuable tool for studying HIV replication and potential therapeutic applications in antiviral research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	950913-56-1
Applications	Nucleoside RT Inhibitor
Formula	C₁₂H₁₅FN₅O₁₂P₃
Molecular Weight	533.19
SMILES	O=[P](O[P](O[P](O)(O)=O)(O)=O)(O)OC[C@]1(O[C@@](C[C@@H]1O)([H])N2C3=NC(F)=NC(N)=C3N=C2)C#C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.