Efinaconazole-d4 is a deuterium-labeled derivative of Efinaconazole, a triazole antifungal agent targeting fungal pathogens. It demonstrates potent in vitro activity against Trichophyton mentagrophytes and Candida albicans, with minimal inhibitory concentrations (MICs) of 0.0039 μg/mL and 0.00098 μg/mL, respectively. This stable isotope compound is valuable for pharmacokinetic studies and mechanistic research involving fungal infections and dermatophyte activity.
Efinaconazole-d4 is a deuterium-labeled derivative of Efinaconazole, a triazole antifungal agent targeting fungal pathogens. It demonstrates potent in vitro activity against Trichophyton mentagrophytes and Candida albicans, with minimal inhibitory concentrations (MICs) of 0.0039 μg/mL and 0.00098 μg/mL, respectively. This stable isotope compound is valuable for pharmacokinetic studies and mechanistic research involving fungal infections and dermatophyte activity.
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