Fig. 1 · Structure
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Eflornithine hydrochloride
Ornithine Decarboxylase Inhibitor
Eflornithine hydrochloride is a selective and irreversible inhibitor of ornithine decarboxylase, an enzyme implicated in polyamine metabolism. This compound demonstrates significant biological activity in inhibiting cell proliferation and is utilized in research related to African trypanosomiasis and the management of excessive facial hair growth in women. Its mechanism of action makes it a valuable tool in studies examining cellular growth regulation and therapeutic interventions for related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 68278-23-9 |
| Applications | Ornithine Decarboxylase Inhibitor |
| Formula | C6H13ClF2N2O2 |
| Molecular Weight | 218.63 |
| Synonyms | DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride |
| SMILES | NC(CCCN)(C(F)F)C(O)=O.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.