Fig. 1 · Structure
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Eflornithine
Ornithine Decarboxylase Inhibitor
Eflornithine is a selective, irreversible inhibitor of the enzyme ornithine decarboxylase. This compound demonstrates significant biological activity in the treatment of African trypanosomiasis, also known as sleeping sickness, as well as in managing excessive facial hair growth in women. Its ability to modulate polyamine synthesis makes it a valuable reagent in research related to cancer biology and dermatological studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 70052-12-9 |
| Applications | Ornithine Decarboxylase Inhibitor |
| Formula | C6H12F2N2O2 |
| Molecular Weight | 182.17 |
| Synonyms | DFMO; MDL71782; RMI71782; α-difluoromethylornithine |
| SMILES | NC(CCCN)(C(F)F)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.