Fig. 1 · Structure

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Efruxifermin

Fc-FGF21 Fusion Protein

Efruxifermin is an Fc-FGF21 fusion protein comprising a human IgG1 Fc domain linked to a modified human FGF21. This compound exhibits a prolonged half-life and increased receptor affinity relative to native human FGF21. Efruxifermin is primarily utilized in research focused on non-alcoholic steatohepatitis, providing insights into metabolic regulation and potential therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2375240-92-7
Applications Fc-FGF21 Fusion Protein
Molecular Weight 91.863 kDa
Synonyms AKR-001; AMG-876

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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